サン調剤薬局

滋賀県守山市にある『サン調剤薬局』のブログ

投稿時間 : 12時02分10秒

カテゴリー : 指定なし(ブログ)

ジャンル : 日記

滋賀県守山市サン調剤薬局西川です。
一時よりは減ったもののインフルエンザの流行が続いてますね。
こんなに感染しやすいB型って、どうなってるんでしょう。

研修日時 平成30年1月30日13:00~13:30
研修タイトル エフィエント
1、エフィエントの用法用量は以下の通りである。
  通常、成人には、投与開始日に20㎎を1回投与し、その後、維持用量として1日1回3.75mgを経口投与。
  原則、アスピリンと併用する。
  PCI施行前に3.75㎎を5日程度投与されている場合、初回の20㎎投与は必須ではない。
  (投与開始5日間で定常状態に達すると想定されるため。)
  2.5㎎の規格は過去に出血傾向があった人や低体重の人に使用されることあり。
2、同種薬の開発の歴史は以下の通りで、開発が進み肝機能異常などの副作用が少なくなった。
  1981年 チクロピジン
  2006年 クロピドグレル
  2014年 プラスグレル
3、プラスグレルの特徴は以下の通りである。
 ・服用開始早期から、血小板抑制作用を示す。
 ・欧米人より日本人に多いとされるCYP2C19の遺伝子多型に影響されない。チクロピジンやクロピドグレルは
  遺伝子多型があると、代謝異常があり薬が効いていない可能性がある。
 ・プラスグレルは初回投与から2~4時間後から、安定した血小板凝集抑制作用を示す。クロピドグレルは肝で
  2回代謝を受けて活性代謝物となるが、プラスグレルは1回で活性代謝物となる。それが立ち上がりの早さに
  関係している。

前回研修会報告 前立腺肥大症に禁忌の薬http://blog.cabrain.net/CN112049/article/id/104241.html
局内研修会履歴 http://www.myph.jp/sun_pharm/pc/free2.html
薬局HP http://www.myph.jp/sun_pharm/pc/index.html
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